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You are here:Home » Antibodies » Abs to Enzymes, Polymerase » Anti -DNA Polymerase, eta (POLH, RAD30 Homolog A, Xeroderma Pigmentosum Variant Type Protein, RAD30, RAD30A, XPV)

Anti -DNA Polymerase, eta (POLH, RAD30 Homolog A, Xeroderma Pigmentosum Variant Type
Protein, RAD30, RAD30A, XPV)

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Specifications

Clone Host Grade Applications
Polyclonal Mouse Purified B IC IF
DNA polymerase eta is specifically involved in DNA repair. It plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. It also plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. It targets POLI to replication foci.
Catalog #D3935-33K
ApplicationsSuitable for use in Western Blot, Immunocytochemistry and Immunofluorescence. Other applications not tested.
Recommended DilutionImmunocytochemistry/Immunofluorescence: 10ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, 11c7entrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified.
ImmunogenPOLH (NP_006493.1, 1-713aa) full-length human protein.
SpecificityRecognizes human POLH.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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