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Abs to DEAH Box Proteins
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Anti -DHX38 (DEAH (Asp-Glu-Ala-His) Box 38, DDX38, KIAA0224, PRPF16)
Anti -DHX38 (DEAH (Asp-Glu-Ala-His) Box 38, DDX38, KIAA0224, PRPF16)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IP |
|
| DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a member of the DEAD/H box family of splicing factors. This protein resembles yeast Prp16 more closely than other DEAD/H family members. It is an ATPase and essential for the catalytic step II in pre-mRNA splicing process. | | | Catalog # | D6510-58B | | Applications | Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | ~0.2mg/ml | | Form | Supplied as a liquid in TBS, pH 7.2, 0.1% BSA, 0.1% sodium azide. | | Purity | Purified by peptide immunoaffinity chromatography. | | Immunogen | The epitope recognized maps to a region between residue 1200 and the C-terminus (residue 1227) of human DEAH (Asp-Glu-Ala-His) Box Protein 38 using the numbering given in entry NP_054722.2 (GeneID 9785). | | Specificity | This antibody is specific to the human and mouse DHX38 protein. Species Crossreactivity: Human and mouse. Other species have not been tested. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | DHX-38, DEAH (Asp-Glu-Ala-His) Box Polypeptide 38, DDX-38, DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 38, PRP16, Pre-mRNA Splicing Factor 16 |
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