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You are here:Home » Antibodies » Abs to Drugs » Anti -Digoxin

Anti -Digoxin

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Highly Purified E RIA
Digoxin is a glycoside extracted from the foxglove plant Digitalis lanata. Its primary mechanism of action is to inhibit alpha subunits of the Na+/K+ ATPase pump located in the plasma membrane of human myocytes. This inhibition leads to an increase in intracellular calcium concentration and an increase in myocardial contraction. Digoxin also results in a decrease of electrical impulse conduction through the AV node. Digoxin is widely used in the treatment of various heart conditions, namely atrial fibrillation, atrial flutter and atrial tachycardia.
Catalog #D8030-11D
ApplicationsSuitable for use in ELISA and RIA. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No10B2747
HostMouse
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by DEAE chromatography.
ImmunogenDigoxin conjugated to bovine serum albumin
SpecificityRecognizes digoxin and also reacts wih digitoxin.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesLanoxin


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