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You are here:Home » Antibodies » Abs to Enzymes, Protease (Proteinase, Peptidase) » Anti -Dipeptidyl Peptidase 10, aa765-779 (DPP10, DPL2, DPPY, DPRP-3, DPRP3, KIAA1492)

Anti -Dipeptidyl Peptidase 10, aa765-779 (DPP10, DPL2, DPPY, DPRP-3, DPRP3, KIAA1492)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
A novel gene, DPP10, encodes a homolog of dipeptidyl peptidases (DPPs) that cleave terminal dipeptides from cytokines and chemokines, and it presents a potential new target for asthma therapy. The DPP10 protein shares features with members of the S9B family of DPP serine proteases, which includes DPP4, a widely expressed enzyme that plays a central role in chemokine processing as part of the innate immune system. The locus displays a complex pattern of transcript splicing, with eight alternate first exons; four of which localize within the LD block strongly associated with asthma.
Catalog #D8065-32C
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA (peptide): 1:32,000
Western Blot: 0.1-0.3ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris-saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
PurityPurified by immunoaffinity chromatography
ImmunogenSynthetic peptide, C-DEGHNVSEKSKYHL, representing the Internal of the human protein (residues 765-779), according to NP_065919.2; NP_001004360.1.
SpecificityRecognizes human Dipeptidyl Peptidase 10 . Predicted to react with Chicken (86% identity with immunogen), Chimpanzee (100% identity with immunogen), bovine (100% identity with immunogen) and canine (92% identity with immunogen) due to sequence homology.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesDPL2, DPPY, DPRP-3, DPRP3, KIAA1492


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