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You are here:Home » Antibodies » Abs to Infectious Disease Diphtheria » Anti -Diphtheria Toxin, A Subunit (Corynebacterium diphtheriae Toxoid A, DT)

Anti -Diphtheria Toxin, A Subunit (Corynebacterium diphtheriae Toxoid A, DT)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E
DT catalyzes the ADP-ribosylation of eukaryotic aminoacyl-transferase II (EF-2) using NAD as a substrate. This reaction forms the basis for its toxicity toward eukaryotic organisms. The toxin is secreted as a single polypeptide chain of about 63kD, it is then processed to form A and B fragments both of which appear to be required for toxicity.
Catalog #D8065-43D
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No10B2750
HostMouse
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, 0.09% sodium azide, 1% BSA.
PurityPurified by Protein A affinity chromatography.
ImmunogenNative
SpecificityRecognizes diphtheria toxin (DT), secreted by certain strains of Corynebacterium diphtheriae. Specific for both the free and bound A subunit of diphtheria toxin.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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