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You are here:Home » Antibodies » Abs to Disease Markers » Anti -DISC1 (Disrupted in Schizophrenia 1, RP4-730B13.1, KIAA0457, SCZD9)

Anti -DISC1 (Disrupted in Schizophrenia 1, RP4-730B13.1, KIAA0457, SCZD9)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
The DISC1 protein is widely expressed in normal tissues. It is involved in neurite outgrowth and
cortical development through its interaction with a variety of proteins including lissencephaly-1 (LIS1), NudeE- like (NUDEL) and phosphodiesterase 4B. DISC1 has been associated with the risk of schizophrenia, schizoaffective disorder, bipolar disorder, major depression and Asperger syndrome.
Catalog #D8066-83D
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1-2ug/ml detects bands of approximately 95-100kD 3T3 in cell lysates.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.
PurityPurified by affinity chromatography.
ImmunogenA 13 amino acid peptide located near the amino terminal region of human DISC1.
SpecificityRecognizes disrupted in schizophrenia 1 (DISC1), 93kD protein located in the nucleus, cytoplasm and mitochondria. Species Crossreactivity: mouse
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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