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You are here:Home » Antibodies » Abs to Disease Markers » Anti -DISC1 (Disrupted in Schizophrenia 1, RP4-730B13.1, KIAA0457)

Anti -DISC1 (Disrupted in Schizophrenia 1, RP4-730B13.1, KIAA0457)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified B
The DISC1 protein is widely expressed in normal tissues. It is involved in neurite outgrowth and cortical development through its interaction with a variety of proteins including lissencephaly-1 (LIS1), NudeE- like (NUDEL) and phosphodiesterase 4B. DISC1 has been associated with the risk of schizophrenia, schizoaffective disorder, bipolar disorder, major depression and Asperger syndrome.
Catalog #D8066-83E
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 0.1-0.3ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHuman Brain (Hippocampus) lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-HSEDKRKTPLKVLE , from the internal region of the protein sequence according to NP_001012977; NP_001012975.1; NP_061132.2.
SpecificityRecognizes human DISC1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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