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Abs to Enzymes, Methyltransferase
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Anti -DMAP1 (DNA Methyltransferase 1-Associated Protein 1, DNMAP1, DNMTAP1, DNMT1-Associated Protein 1, MAT1-Mediated Transcriptional Repressor)
Anti -DMAP1 (DNA Methyltransferase 1-Associated Protein 1, DNMAP1, DNMTAP1,
DNMT1-Associated Protein 1, MAT1-Mediated Transcriptional Repressor)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E B |
|
| DNA methyltransferases methylate the 5-position of cytosine in the context of CpG dinucleotides. DNA methylation is crucial for normal embryonic development, imprinting, and X-chromosome inactivation. DNA methyltransferase 1 associated protein (DMAP1) has been shown to interact directly with the N-terminus of DNA Methyltransferase 1 (Dnmt1) throughout DNA replication during S phase. DMAP1 has also been identified as a critical gene product in myotonic dystrophy. | | | Catalog # | D8073-02A | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | Western Blotting: 1:1000-1:2000 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Goat | | Source | Human | | Concentration | As reported | | Form | As reported | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | A 25 amino acid synthetic peptide, which represented a portion of human DNA methyltransferase 1-associated protein 1 encoded in part by exons 2 and 3 (LocusLink ID 55929). | | Specificity | This antibody is specific for human DMAP1. Species Crossreactivity: Recognizes human. Other species have not been tested. Reactivity with mouse is likely owing to 25/25 identical residues between mouse DMAP1 and the peptide used for this production. May react with Zebrafish (22/25 identical residues). | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | DKFZp686L09142, EAF2, FLJ11543, KIAA1425, SWC4 |
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