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Anti -DOK1, CT (Docking Protein 1 62kD, Downstream Of Tyrosine Kinase 1, MGC117395, MGC138860, p62(dok), P62DOK, pp62)
Anti -DOK1, CT (Docking Protein 1 62kD, Downstream Of Tyrosine Kinase 1, MGC117395,
MGC138860, p62(dok), P62DOK, pp62)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IH |
|
| Docking proteins interact with receptor tyrosine kinase to mediate particular biological responses. DOK1 is a major substrate for a range of tyrosine kinases including c-kit, v-abl, v-Fms, v-Src along with activated EGF, PDGF, IGF, VEGF and insulin receptors. | | | Catalog # | D8080-01J | | Research indicates that DOK1 is a negative regulator of the insulin signalling pathway. | | Dok1 is expressed in a range of human tissues including the pancreas, heart and spleen, it is also expressed by both resting and activated peripheral blood T-cells. | | Applications | Suitable for use in Immunohistochemistry (frozen) and Western Blot. Other applications not tested. | | Recommended Dilution | Immunohistochemistry (frozen): 2ug/ml | | Western Blot: 0.5-1ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, 0.02% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | A peptide corresponding to aa near the carboxy terminus of human DOK1. | | Specificity | Recognizes human DOK1 (Downstrean of tyrosine kinase). | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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