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You are here:Home » Antibodies » Abs to Signal Transduction » Anti -DOK1, CT (Docking Protein 1 62kD, Downstream Of Tyrosine Kinase 1, MGC117395, MGC138860, p62(dok), P62DOK, pp62)

Anti -DOK1, CT (Docking Protein 1 62kD, Downstream Of Tyrosine Kinase 1, MGC117395,
MGC138860, p62(dok), P62DOK, pp62)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
Docking proteins interact with receptor tyrosine kinase to mediate particular biological responses. DOK1 is a major substrate for a range of tyrosine kinases including c-kit, v-abl, v-Fms, v-Src along with activated EGF, PDGF, IGF, VEGF and insulin receptors.
Catalog #D8080-01J
Research indicates that DOK1 is a negative regulator of the insulin signalling pathway.
Dok1 is expressed in a range of human tissues including the pancreas, heart and spleen, it is also expressed by both resting and activated peripheral blood T-cells.
ApplicationsSuitable for use in Immunohistochemistry (frozen) and Western Blot. Other applications not tested.
Recommended DilutionImmunohistochemistry (frozen): 2ug/ml
Western Blot: 0.5-1ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenA peptide corresponding to aa near the carboxy terminus of human DOK1.
SpecificityRecognizes human DOK1 (Downstrean of tyrosine kinase).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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