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You are here:Home » Antibodies » Abs to Binding Proteins » Anti -DOK5 (Docking Protein 5, Downstream Of Tyrosine Kinase 5, Insulin Receptor Substrate 6, IRS-6, IRS6, C20orf180)

Anti -DOK5 (Docking Protein 5, Downstream Of Tyrosine Kinase 5, Insulin Receptor Substrate
6, IRS-6, IRS6, C20orf180)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified B IH
DOK5 represent a new signaling protein which has a potential role in insulin and IGF-1 action. This is an adapter proteins involved in signal transduction. DOK5 genes expressed in T cells and its expression is highest in skeletal muscle. This protein is tyrosine-phosphorylated in response to insulin and IGF-1 in transfected cells, It neither associates with these Src homology 2 domains nor activates MAPK.
Catalog #D8080-05D
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 0.1ug/ml
Immunohistochemistry (paraffin): 1ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHuman Kidney lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to CLHRTETFPAYRSEH, from the C-terminus of the protein sequence according to NP_060901.
SpecificityRecognizes human DOK5. Species sequence homology: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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