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Anti -DOK5 (Docking Protein 5, Downstream Of Tyrosine Kinase 5, Insulin Receptor Substrate 6, IRS-6, IRS6, C20orf180)
Anti -DOK5 (Docking Protein 5, Downstream Of Tyrosine Kinase 5, Insulin Receptor Substrate 6, IRS-6, IRS6, C20orf180)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
B IH |
|
| DOK5 represent a new signaling protein which has a potential role in insulin and IGF-1 action. This is an adapter proteins involved in signal transduction. DOK5 genes expressed in T cells and its expression is highest in skeletal muscle. This protein is tyrosine-phosphorylated in response to insulin and IGF-1 in transfected cells, It neither associates with these Src homology 2 domains nor activates MAPK. | | | Catalog # | D8080-05D | | Applications | Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 0.1ug/ml | | Immunohistochemistry (paraffin): 1ug/ml | | Optimal dilutions to be determined by the researcher. | | Positive Control | Human Kidney lysate | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to CLHRTETFPAYRSEH, from the C-terminus of the protein sequence according to NP_060901. | | Specificity | Recognizes human DOK5. Species sequence homology: mouse and rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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