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You are here:Home » Antibodies » Abs to Enzymes, Decarboxylase » Anti -Dopamine Decarboxylase (DOPA Decarboxylase, DDC, DOPA, Aromatic-L-amino-acid Decarboxylase, AADC)

Anti -Dopamine Decarboxylase (DOPA Decarboxylase, DDC, DOPA, Aromatic-L-amino-acid
Decarboxylase, AADC)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
DOPA Decarboxylase (aromatic L-amino acid decarboxylase, AADC; DDC) catalyzes the second reaction in the biosynthesis of catecholamines and serotonin (Waymire and Haycock, 2002; Berry et al., 1996; Haycock et al., 2003). It is also involved in the biosynthesis of trace amines. DDC antibodies can therefore be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinsonís disease and drug abuse (Kish et al., 2001; Zhu et al., 2000; Zhu et al., 1999).
Catalog #D9013-01J
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000
Optimal dilutions to be determined by the researcher.
Positive ControlBovine adrenal medulla lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid 10mM HEPES, pH 7.5, 150mM sodium chloride, 100ug per ml BSA, 50% glycerol.
PurityPurified by immunoaffinity chromatography.
ImmunogenHuman DOPA Decarboxylase.
SpecificityRecognizes human DOPA Decarboxylase. Species Crossreactivity: bovine.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesDopa Decarboxylase (Aromatic L-amino Acid Decarboxylase), EC=4.1.1.28


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