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You are here:Home » Antibodies » Abs to Transport Proteins » Anti -Dopamine Transporter (DA Transporter, DAT, DAT 1, DAT1, Sodium-dependent Dopamine Transporter, Solute Carrier Family 6 (Neurotransmitter Transporter Dopamine) Member 3, SLC6A3)

Anti -Dopamine Transporter (DA Transporter, DAT, DAT 1, DAT1, Sodium-dependent Dopamine
Transporter, Solute Carrier Family 6 (Neurotransmitter Transporter Dopamine) Member 3,
SLC6A3)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rat Supernatant B IH
The transmembrane dopamine transporter (DAT) is located on the presynaptic nerve terminal and is responsible for terminating dopaminergic transmission by transporting dopamine from the synaptic cleft into the dopaminergic neuron (reuptake). Dopaminergic pathways have been strongly implicated in reward and addiction, motivation, alcoholism, ADHD and degenerative motor diseases such as Parkinsonís, Huntingtonís and Chorea.
Catalog #D9020-01J
ApplicationsSuitable for use in Immunohistochemistry and Western Blot. Other applications not tested.
Recommended DilutionsImmunohistochemistry (Frozen): 1:1,000-1:10,000
Western Blot: Recognizes a diffuse band at ~70-85kD on extracts from human caudate, putamen and nucleus accumbens
Optimal dilutions to be determined by the researcher.
Positive ControlsBrain (caudate, putamen and nucleus accumbens)
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No10B2323
HostRat
SourceHuman
ConcentrationNot Determined
FormSupplied as a liquid. No preservative added.
PuritySupernatant
ImmunogenN-terminus of human dopamine transporter fused to Glutathione S-transferase.
SpecificityRecognizes the human dopamine transporter, N-terminus. Does not crossreact with serotonin and norepinephrine transporters. Species Crossreactivity: monkey, mouse and rat
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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