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Anti -DPM1 (Dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit, RP23-391M18.1, AI118379, AI194292, OTTMUSP00000017164, dolichol monophosphate mannose synthase, dolichyl-phosphate mannosyltransferase polypeptide 1)
Anti -DPM1 (Dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit,
RP23-391M18.1, AI118379, AI194292, OTTMUSP00000017164, dolichol monophosphate mannose
synthase, dolichyl-phosphate mannosyltransferase polypeptide 1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
B |
|
| Dolichol-phosphate mannose (DPM1) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Defective surface expression of GPI-anchored proteins occurs when there is a lack of DPM1. DPM1 is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2. | | | Catalog # | D9150-79 | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | ELISA: 1:64,000 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Rat | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA. | | Purity | Purified by affinity chromatography. | | Immunogen | Synthetic peptide corresponding to PQGRSSRQDKYS-C from the N-Terminus of rat DPM1 (NP_034202.1). | | Specificity | Recognizes rat DPM1. Sequence Homology: mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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