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You are here:Home » Antibodies » Abs to Enzymes, Transferase » Anti -DPM2 (Dolichol-phosphate (beta-D) Mannosyltransferase 2, RP23-255P20.5, AW557993, R75484, OTTMUSP00000012854)

Anti -DPM2 (Dolichol-phosphate (beta-D) Mannosyltransferase 2, RP23-255P20.5, AW557993,
R75484, OTTMUSP00000012854)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E
Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. The protein encoded by this gene is a hydrophobic protein that contains 2 predicted transmembrane domains and a putative ER localization signal near the C terminus. This protein associates with DPM1 in vivo and is required for the ER localization and stable expression of DPM1 and also enhances the binding of dolichol-phosphate to DPM1.
Catalog #D9150-80
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:16000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostGoat
SourceMouse
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris, pH 7.2, 0.5% BSA, 0.02% sodium azide.
PurityPurified by affinity chromatography.
ImmunogenSynthetic peptide with sequence C-YVMLKSQKITKKAQ, from the C-Terminus of murine DPM2.
SpecificityRecognizes mouse DPM2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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