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You are here:Home » Antibodies » Abs to Disease Markers » Anti -DSCAM (Down Syndrome Cell Adhesion Molecule, CHD2)

Anti -DSCAM (Down Syndrome Cell Adhesion Molecule, CHD2)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
The Dscam family of cell surface proteins mediates recognition events between neurons that play an essential role in the establishment of neural circuits in many organisms. Interneurons form synaptic connections with retinal ganglion cells in specific layers. Dscam and DscamL are expressed in different subsets of interneurons and ganglion cells. Interestingly, interneurons and ganglion cells that target to the same layer, express the same Dscam protein.
Catalog #D9635-51D
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:16,000
Western Blot: 2-6ug/ml, human brain, cerebellum lysates on ~170kD bands
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-DSWDSAQRTKDVSPQ, from human DSCAM, at the internal region of the protein (NP_001380.2, NP_996770.1).
SpecificityRecognizes human DSCAM. Species sequence homology: Canine, mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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