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You are here:Home » Antibodies » Abs to Signal Transduction » Anti -Dishevelled 2, phosphorylated (pT224) (DVL2, DSH homolog 2)

Anti -Dishevelled 2, phosphorylated (pT224) (DVL2, DSH homolog 2)

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IP
Dishevelled 2 is a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. Dishevelled 2 is a 90kD protein that undergoes posttranslational phosphorylation to form a 95kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans.
Catalog #D9641-02
ApplicationsSuitable for use in Western Blot and Immunoprecipitation. Other applications have not been tested.
Recommended Dilutions
Western Blot: 1:1000-1:10,000
Immunoprecipitation: 1:10-1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
Clone NoEPNCIR146
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in PBS, pH 7.2, 0.05% BSA, 0.01% sodium azide, 50% glycerol.
PuritySupernatant
ImmunogenA phospho specific peptide corresponding to residues surrounding Threonine 224 of human Dishevelled 2.
SpecificityRecognizes human Dishevelled 2 phosphorylated at Threonine 224. Species crossreactivity: Mouse, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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