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You are here:Home » Antibodies » Abs to Transcription Factors, Zinc (Ring) Finger » Anti -DTX2 (RING Finger Protein 58, Protein Deltex-2, Deltex2, hDTX2, KIAA1528, RNF58)

Anti -DTX2 (RING Finger Protein 58, Protein Deltex-2, Deltex2, hDTX2, KIAA1528, RNF58)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E
DTX2 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. It probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. It mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. It functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
Catalog #D9644-02A
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:32,000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-EKLSTASGYSDVTD, from DTX2, at the internal region of the protein (NP_065943.2, NP_001096066.1).
SpecificityRecognizes DTX2. Species sequence homology: Bovine, human and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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