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You are here:Home » Antibodies » Abs to Enzymes, Phosphatase » Anti -DUSP4 (Dual Specificity Protein Phosphatase 4, Dual Specificity Protein Phosphatase hVH2, HVH2, Mitogen-activated Protein Kinase Phosphatase 2, MAP Kinase Phosphatase 2, MKP2, MKP-2, TYP, VH2)

Anti -DUSP4 (Dual Specificity Protein Phosphatase 4, Dual Specificity Protein Phosphatase
hVH2, HVH2, Mitogen-activated Protein Kinase Phosphatase 2, MAP Kinase Phosphatase 2,
MKP2, MKP-2, TYP, VH2)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, ERK2 and JNK, is expressed in a variety of tissues, and is localized in the nucleus. Two alternatively spliced transcript variants, encoding distinct isoforms, have been observed for this gene. In addition, multiple polyadenylation sites have been reported.
Catalog #D9840-08C
ApplicationsSuitable for use in Western Blot and Dot Blot. Other applications not tested.
Recommended DilutionsOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No8C121
HostMouse
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 1% BSA, 0.05% sodium azide
PurityPurified by Protein G affinity chromatography.
ImmunogenPartial recombinant protein corresponding to human DUSP4
SpecificityRecognizes human DUSP4.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesDual Specificity Phosphatase 4, EC=3.1.3.16, EC=3.1.3.48


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