Anti -DUSP16, NT (Dual Specificity Protein Phosphatase 16, KIAA1700, Mitogen-activated
Protein Kinase Phosphatase 7, MAP Kinase Phosphatase 7, MKP7, MKP-7)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Purified |
E IH |
|
| DUSP16 is involved in the inactivation of MAP kinases. The activation of mitogen-activated protein kinase (MAPK) cascades transduces various extracellular signals to the nucleus to induce gene expression, cell proliferation, differentiation, cell cycle arrest, and apoptosis. For full activation of MAPKs, dual-specificity kinases phosphorylate both threonine and tyrosine residues in MAPK TXY motifs. MKPs are dual-specificity phosphatases that dephosphorylate the TXY motif, thereby negatively regulating MAPK activity. | | | Catalog # | D9840-52F | | Applications | Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | ELISA: 1:32,000 | | Immunohistochemistry (Formalin fixed paraffin embedded): 2.5ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in 0.5mg/ml TBS, 0.02% sodium azide, pH 7.3, 0.5% BSA. | | Purity | Purified by ammonium sulfate precipitation. | | Immunogen | Synthetic peptide corresponding to human DUSP16 at N-terminal (NP_085143.1) | | Specificity | Recognizes human DUSP16. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Dual Specificity Phosphatase 16, EC=3.1.3.16, EC=3.1.3.48, FLJ36298, FLJ40991, MGC129701, MGC129702 |
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