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You are here:Home » Antibodies » Abs to Enzymes, Phosphatase » Anti -DUSP16 (Dual Specificity Protein Phosphatase 16, KIAA1700, Mitogen-activated Protein Kinase Phosphatase 7, MAP Kinase Phosphatase 7, MKP7, MKP-7)

Anti -DUSP16 (Dual Specificity Protein Phosphatase 16, KIAA1700, Mitogen-activated Protein
Kinase Phosphatase 7, MAP Kinase Phosphatase 7, MKP7, MKP-7)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E IH
DUSP16 is a 665aa novel mitogen-activated protein kinase phosphatase belonging to the non-receptor class of the protein-tyrosine phosphatase family with a rhodanese-like domain, protein tyrosine phosphatase catalytic domain and a long terminal stretch containing nuclear export and localization signal. DUSP16 are dual-specificity phosphatases that dephosphorylate the TXY motif of MAPK TXY motifs, thereby inactivating MAP kinases. DUSP16 is ubiquitously expressed and behaves both as a nuclear shuttle and as a phosphatase. It binds to and inactivates p38 MAPK and JNK/SAPK, p38 alpha and -beta but not gamma or delta and ERK.
Catalog #D9840-52H
ApplicationsSuitable for use in ELISA and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:32,000
Immunohistochemistry (Paraffin): 2-4ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to AHEMIGTQIVTER-C, from human DUSP16, at N-terminal (NP_085143.1).
SpecificityRecognizes human DUSP16. Species sequence homology: Bovine, canine, mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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