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Specifications

Ecotin is a serine protease inhibitor that is found in the periplasm of Escherichia coli. It has a very broad range of inhibition including the pancreatic serine proteases trypsin and chymotrypsin, human leukocyte and porcine elastase and rat mast cell chymase. Ecotin is regarded as a potent, tight-binding, reversible inhibitor of Factor Xa. Ecotin does not inhibit the human plasma proteases thrombin, tissue factor-factor VIIa, Factor XIa, Protein C, plasmin or tPA.
Catalog #	E0390
Kinetic Data	1:1 inhibition of trypsin
Storage and Stability	For long-term storage, aliquot to avoid repeated freezing and thawing and freeze at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 12 months.
Molecular Weight	16kD
Source	E. coli
Purity	98% by SDS PAGE
Concentration	~2mg/ml (120mM)
Form	Supplied as liquid in 1mM HCl.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.