Anti -EDG1 (Endothelial Cell Differentiation Gene 1, EDG 1, EDG-1, Endothelial
Differentiation Sphingolipid G Protein Coupled Receptor 1, CHEDG1, D1S3362, G Protein
Coupled Sphingolipid Receptor, Sphingosine 1-phosphate Receptor Edg-1, Sphingosine
1-phosphate R
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
B IH FC |
|
| EDG1, a Lysophospholipid/Lysosphingolipid Receptor, binds sphingosine-1-phosphate and may control cell proliferation, survival, and suppression of apoptosis. Overexpression of EDG-1 leads to increased cell-cell aggregation and overexpression of cadherins. EDG-1 transcripts have been reported to be present in embryonic and adult brain, lung alveolar macrophages, vascular smooth muscle cells, endothelial cells, fibroblasts, melanocytes, and TAg-Jurkat T cells, but to be absent from breast cancer cell lines. ESTs have been isolated from brain, breast, heart, heart/melanocyte/uterus, kidney, liver, liver/spleen, lung, nerve, placenta, prostate, tonsil, uterus, and vessel libraries. | | | Catalog # | E2208-01F | | Applications | Suitable for use in Flow Cytometry, Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Flow Cytometry: 1:50-1:200 | | Western Blot: 1:100-1:1000 | | Immunohistochemistry (Paraffin): 1:50 | | Optimal dilutions to be determined by the researcher. | | Hybridoma | Mouse myeloma fused with spleen cells from a mouse immunized with human recombinant Endothelial Differentiation Gene 1 (EDG1) protein. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 9G58 | | Host | Mouse | | Source | Human | | Concentration | ~0.2mg/ml | | Form | Supplied as a lyophilized powder. No preservatives added. Reconstitute with 500ul sterile PBS. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Human recombinant EDG-1 protein. | | Specificity | Recognizes human EDG-1. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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