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You are here:Home » Antibodies » Abs to G Protein Receptors » Anti -EDG1 (Sphingosine 1-phosphate Receptor 1, S1P Receptor 1, S1P1, Endothelial Differentiation G-protein Coupled Receptor 1, Lysophospholipid Receptor B1, Sphingosine 1-phosphate Receptor Edg-1, S1P Receptor Edg-1, CD363, S1pr1, Lpb1)

Anti -EDG1 (Sphingosine 1-phosphate Receptor 1, S1P Receptor 1, S1P1, Endothelial
Differentiation G-protein Coupled Receptor 1, Lysophospholipid Receptor B1, Sphingosine
1-phosphate Receptor Edg-1, S1P Receptor Edg-1, CD363, S1pr1, Lpb1)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified IH FC
EDG-1 also called S1P1 or S1PR1 is a widely expressed, 37-40kD, G protein coupled receptor within the S1P subfamily of the EDG family. EDG-1 is one of five receptors for the bioactive lipid S1P and mediates most of S1P effects on angiogenesis, vascular maturation, and cell migration, especially T cell egress from lymphoid organs. Human and mouse EDG-1 share 84% aa identity within the N-terminal extracellular portion used as an immunogen.
Catalog #E2208-03B
ApplicationsSuitable for use in Flow Cytometry and Immunohistochemistry. Other applications not tested.
Recommended DilutionFlow Cytometry: 2.5ug labels 10e6
Immunohistochemistry: 8-25ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2A
Clone No12K85
HostRat
SourceMouse
Concentration~0.5mg/ml after reconstitution
FormSupplied as a lyophilized powder in PBS, trehalose. Reconstitute with sterile PBS to 0.5mg/ml.
PurityPurified by Protein A/G affinity chromatography.
ImmunogenSynthetic peptide corresponding to mouse EDG1.
SpecificityRecognizes mouse EDG1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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