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You are here:Home » Biochemicals » Biochem-Drugs/Analogues » Elcatonin (Ser-Asn-Leu-Ser-Thr-Asu-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro- Arg-Thr-Asn-Val-Gly-Ala-Gly-Thr-Pro-NH2)

Elcatonin
(Ser-Asn-Leu-Ser-Thr-Asu-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-
Arg-Thr-Asn-Val-Gly-Ala-Gly-Thr-Pro-NH2)

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Specifications

Elcatonin is a Calcitonin derivative which is transformed from eel s calcitonin by changing the S-S bond into the stable C-N bond. It inhibits the absorption and autolysis of bones, thus leads to blood calcium descending. In addition, it inhibits the bone salts dissolving and transferring and promotes the excretion of calcium and phosphorus in urine. Meanwhile, it inhibits renal tubules reabsorbing calcium, phosphorus and sodium and keeps blood calcium at normal level. It is mainly used for remitting or eliminating the pain caused by Osteoporosis. Elcatonin synthetic is a single, non-glycosylated polypeptide chain containing 31aa.
Catalog #E2235-70
AA Sequence Ser-Asn-Leu-Ser-Thr-Asu-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro- Arg-Thr-Asn-Val-Gly-Ala-Gly-Thr-Pro-NH2.
Molecular Weight3363.2D
Biological Activity6065 IU/mg
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number60731-46-6
Molecular FormulaC148H244N42O47
Molecular Weight3363.2D
SourceSynthetic
Purity~95% (SDS-PAGE, HPLC)
ConcentrationNot determined
FormSupplied as a lyophilized powder. Reconstitute with sterile dH2O to 100ug/ml.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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