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You are here:Home » Antibodies » Abs to Translation Initiation Factors » Anti -EIF2C2 (Eukaryotic translation initiation factor 2C, 2, AGO2, Argonaute2, eIF2C 2, eIF-2C 2, Eukaryotic translation initiation factor 2C 2, hAgo2, MGC3183, PAZ Piwi domain protein, PPD, Protein argonaute-2, Protein slicer, Q10)

Anti -EIF2C2 (Eukaryotic translation initiation factor 2C, 2, AGO2, Argonaute2, eIF2C 2,
eIF-2C 2, Eukaryotic translation initiation factor 2C 2, hAgo2, MGC3183, PAZ Piwi domain
protein, PPD, Protein argonaute-2, Protein slicer, Q10)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IP
Small non-coding RNAs are important regulators of gene expression in higher eukaryotes. Several classes of small RNAs, including short interfering RNAs (siRNAs), microRNAs (miRNAs) and Piwi-interacting RNAs (piRNAs), have been identified. MicroRNAs are about 21 nucleotides in length and have been implicated in many cellular processes such as development, differentiation and stress response. MicroRNAs regulate gene expression by modulating mRNA translation or stability. MicroRNAs function together with the protein components in the complexes called micro-ribonucleoproteins (miRNPs). Among the most important components in these complexes are Argonaute proteins. There are four members in the mammalian Argonaute family and only Argonaute 2 (Ago2) possesses the Slicer endonuclease activity. Argonaute proteins participate in the various steps of microRNA-mediated gene silencing such as repression of translation and mRNA turnover.
Catalog #E2237-26
ApplicationsSuitable for use in Western Blot and Immunoprecipitation. Other applications not tested.
Recommended DilutionsWestern Blot: 1:1000
Immunoprecipitation: 1:50
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG
Clone No10g170
HostRabbit
SourceMouse
ConcentrationNot Determined
FormSupplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, <0.02% sodium azide, 50% glycerol.
PuritySupernatant
ImmunogenSynthetic peptide corresponding to mouse EIF2C2.
SpecificityRecognizes endogenous levels of total mouse EIF2C2 at ~97kD. Species Crossreactivity: human, rat and monkey
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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