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You are here:Home » Antibodies » Abs to Disease Markers » Anti -Emerin (EDMD, EMD, LEM Domain Containing 5, LEMD5, STA)

Anti -Emerin (EDMD, EMD, LEM Domain Containing 5, LEMD5, STA)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Supernatant B IH
Emerin is the product of the STA gene and is found ubiquitously in tissues. Emerin is found in the highest concentrations in skeletal and cardiac muscle and d e f iciency in its expression is a key factor in Emery- Dreifuss muscular dystrophy.
Catalog #E2257-01E
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:250-1:500.
Immunohistochemistry (Frozen): 1:20-1:40 for 1 hr. at RT
Optimal dilutions to be determined by the researcher.
Positive Control
Western Blot: Sup T cells
Immunohistochemistry: Present in most tissues (eg. tonsil, endometrium, heart and skeletal muscle). Perinuclear staining pattern. Not present in skeletal muscle from patient with Emery-Dreifuss muscular dystrophy.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No4G5
HostMouse
ConcentrationNot determined
FormSupplied as a lyophilized powder in 15mM sodium azide. Reconstitute with 1ml dH2O.
PuritySupernatant
ImmunogenRecombinant protein representing a 222aa region near the amino-terminus of the Emerin protein.
SpecificityRecognizes Emerin. Species Crossreactivity: Human.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesEmery-Dreifuss Muscular Dystrophy


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