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Anti -Emerin (EDMD, EMD, LEM Domain Containing 5, LEMD5, STA)
Anti -Emerin (EDMD, EMD, LEM Domain Containing 5, LEMD5, STA)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Supernatant |
B IH |
|
| Emerin is the product of the STA gene and is found ubiquitously in tissues. Emerin is found in the highest concentrations in skeletal and cardiac muscle and d e f iciency in its expression is a key factor in Emery- Dreifuss muscular dystrophy. | | | Catalog # | E2257-01E | | Applications | Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 1:250-1:500. | | Immunohistochemistry (Frozen): 1:20-1:40 for 1 hr. at RT | | Optimal dilutions to be determined by the researcher. | | Positive Control | | | Western Blot: Sup T cells | | Immunohistochemistry: Present in most tissues (eg. tonsil, endometrium, heart and skeletal muscle). Perinuclear staining pattern. Not present in skeletal muscle from patient with Emery-Dreifuss muscular dystrophy. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 4G5 | | Host | Mouse | | Concentration | Not determined | | Form | Supplied as a lyophilized powder in 15mM sodium azide. Reconstitute with 1ml dH2O. | | Purity | Supernatant | | Immunogen | Recombinant protein representing a 222aa region near the amino-terminus of the Emerin protein. | | Specificity | Recognizes Emerin. Species Crossreactivity: Human. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Emery-Dreifuss Muscular Dystrophy |
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