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You are here:Home » Antibodies » Abs to Disease Markers » Anti -Emerin (Emery-Dreifuss muscular dystrophy, LEM domain containing 5)

Anti -Emerin (Emery-Dreifuss muscular dystrophy, LEM domain containing 5)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum B
Emerin is a LEM domain-containing integral membrane protein of the nuclear membrane in vertebrates. Emerin is known to interact with nuclear lamins, barrier-to-autointegration factor (BAF), nesprin-1 alpha, and a transcription repressor. Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family. It mediates membrane anchorage to the cytoskeleton. Mutations to emerin result in Dreifuss-Emery muscular dystrophy, an X-linked inherited degenerative myopathy.
Catalog #E2257-02A
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000
Optimal dilutions to be determined by the researcher.
Positive ControlA431 cell lysate
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid, 0.05% sodium azide.
PuritySerum
ImmunogenRecombinant protein corresponding to residues surrounding the N-terminus region of Emerin. Cellular Localization: Nucleus inner membrane; Single-pass membrane protein; Nucleoplasmic side.
SpecificityRecognizes human Emerin at and around the N-terminus.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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