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You are here:Home » Antibodies » Abs to Carbohydrates, Glycoproteins » Anti -EMR1 (EGF-like Module Containing Mucin-like Hormone Receptor-like 1, EGF-like Module Receptor 1, EMR1 Hormone Receptor, Cell Surface Glycoprotein F4/80, DD7A5-7, EGF-TM7, F4/80, Gpf480, Lymphocyte Antigen 71, Ly71, TM7LN3)

Anti -EMR1 (EGF-like Module Containing Mucin-like Hormone Receptor-like 1, EGF-like Module
Receptor 1, EMR1 Hormone Receptor, Cell Surface Glycoprotein F4/80, DD7A5-7, EGF-TM7,
F4/80, Gpf480, Lymphocyte Antigen 71, Ly71, TM7LN3)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rat Purified B IP IH FC
EGF-Like Module Containing Mucin-Like Hormone Receptor-Like Sequence 1 (EMR1) is characterized as an Orphan-B GPCR with an unknown ligand. The C-terminus contains seven hydrophobic segments, characteristic of a G protein-coupled receptor. The N-terminus of EMR1 has 6 EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. F4/80 is a monoclonal antibody that recognizes a murine macrophage- restricted cell surface glycoprotein whose amino acid sequence has been determined to be the EMR1 gene. Therefore, the data from this antibody can be used to derive gene expression of mouse EMR1. EMR1 has been reported to be expressed in human peripheral blood mononuclear cells, monocytes, and hematopoietic and solid tumor-derived cell lines. ESTs have been isolated from human normal spleen and mixed liver/spleen libraries and from human kidney, colon, brain, and bone marrow cancer libraries.
Catalog #E2261-41F
ApplicationsSuitable for use in Western Blot, Flow Cytometry, Immunoprecipitation and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (frozen, paraffin): 1:50. Requires proteinase treatment of paraffin sections. Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a
Clone NoBM8
HostRat
SourceMouse
Concentration~0.1mg/ml
FormSupplied as a liquid in 0.02% sodium azide, 0.1% BSA.
PurityPurified
ImmunogenMouse EMR1.
SpecificityRecognizes a 125kD extracellular macrophage membrane molecule, highly restricted to mature macrophage subpopulations residing in tissue.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesEGF-like Module Containing, Mucin-like, Hormone Receptor-like Sequence 1, Pan Macrophages


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