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You are here:Home » Antibodies » Abs to Cell Markers » Anti -ENC1 (Ectoderm-neural cortex protein 1, CCL28 ENC-1, FLJ39259, KLHL35, KLHL37, NRPB, PIG10, TP53I10, Kelch-like protein 37, Nuclear matrix protein NRP/B, p53-induced gene 10 protein)

Anti -ENC1 (Ectoderm-neural cortex protein 1, CCL28 ENC-1, FLJ39259, KLHL35, KLHL37,
NRPB, PIG10, TP53I10, Kelch-like protein 37, Nuclear matrix protein NRP/B, p53-induced
gene 10 protein)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IH IC
DNA damage and/or hyperproliferative signals activate wild-type p53 tumor suppressor protein (TP53), inducing cell cycle arrest or apoptosis. Mutations that inactivate p53 occur in 50% of all tumors. ENC1 is a redox-controlling protein. Reactive oxygen species (ROS) are noted to be potent inducers of apoptosis. Flow cytometric analysis showed that p53 expression induces ROS production, which increases as apoptosis progresses under some conditions. ENC1 is also an actin-binding protein.
Catalog #E2279-65A
ApplicationsSuitable for use in Western Blot, Immunocytochemistry and Immunohistochemistry. Other applications have not been tested.
Recommended Dilutions
Western Blot: 1:1000-1:10,000
Immunohistochemistry: 1:100-1:250
Immunocytochemistry: 1:50-1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
Clone NoEPR5406(B)
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in PBS, pH 7.2, 0.05% BSA, 0.01% sodium azide, 50% glycerol.
PuritySupernatant
ImmunogenSynthetic peptide corresponding to residues in human ENC1.
SpecificityRecognizes human ENC1. Species crossreactivity: Mouse, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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