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You are here:Home » Antibodies » Abs to Enzymes, Endonuclease » Anti -Endonuclease G (EndoG)

Anti -Endonuclease G (EndoG)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Catalog #E2291-40A
Recommended Secondary Reagents Sheep anti Rabbit IgG (Aff. Pur.): HRP
ApplicationsWestern Blotting: 1-2ug/ml
Optimal working dilutions to be determined by researcher.
Western Blotting Detects a band of approximately 35kD in HepG2 and 3T3 cell lysates.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS with 0.02% sodium azide.
PurityPurified IgG was prepared from whole serum by affinity chromatography.
ImmunogenSynthetic peptide GGPRGPGELAKYGLP corresponding to amino acids 55 - 70 of endonuclease G.
SpecificityRecognizes endonuclease G (endoG), a mitochondrion-specific nuclease that translocates to the nucleus and cleaves chromatin DNA during apoptosis endoG i reported to act independently of caspases and may represent a caspase independent apoptotic pathway initiated from the mitochondria. Species Crossreactivity: Human. Expected crossreactivity from sequence similarity mouse, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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