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Anti -Endonuclease G (EndoG)
Anti -Endonuclease G (EndoG)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B |
|
| Catalog # | E2291-40A | | Recommended Secondary Reagents | Sheep anti Rabbit IgG (Aff. Pur.): HRP | | Applications | Western Blotting: 1-2ug/ml | | Optimal working dilutions to be determined by researcher. | | Western Blotting | Detects a band of approximately 35kD in HepG2 and 3T3 cell lysates. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS with 0.02% sodium azide. | | Purity | Purified IgG was prepared from whole serum by affinity chromatography. | | Immunogen | Synthetic peptide GGPRGPGELAKYGLP corresponding to amino acids 55 - 70 of endonuclease G. | | Specificity | Recognizes endonuclease G (endoG), a mitochondrion-specific nuclease that translocates to the nucleus and cleaves chromatin DNA during apoptosis endoG i reported to act independently of caspases and may represent a caspase independent apoptotic pathway initiated from the mitochondria. Species Crossreactivity: Human. Expected crossreactivity from sequence similarity mouse, rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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