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You are here:Home » Antibodies » Abs to Amyloid » Anti -Endoplasmic Reticulum-associated Amyloid Beta-peptide binding protein (ERAB)

Anti -Endoplasmic Reticulum-associated Amyloid Beta-peptide binding protein (ERAB)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
Endoplasmic reticulum-associated amyloid beta-peptide binding protein (ERAB) is a 27kD protein, member of the short-chain dehydrogenase/reductase family, it catalyses the oxidation of a wide variety of fatty acids, alcohols, and steroids. It is constitutively expressed in tissues and overexpressed in neurons affeceted in Alzheimer's disease. ERAB binds amyloid.beta and may be a determining factor in the level of cytotoxicity observed in the brain of Alzheimer's patients.
Catalog #E2291-53B
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:1000
Western Blot: 1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide (DLPNSGGEAQAKKLGNN) corresponding to aa41-57 of human ERAB
SpecificityRecognizes human ERAB
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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