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You are here:Home » Antibodies » Abs to Amyloid » Anti -ERAP2 (Endoplasmic Reticulum Aminopeptidase 2, Leukocyte-derived Arginine Aminopeptidase, L-RAP, LRAP)

Anti -ERAP2 (Endoplasmic Reticulum Aminopeptidase 2, Leukocyte-derived Arginine
Aminopeptidase, L-RAP, LRAP)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Preferentially hydrolyzes the basic residues Arg and Lys.
Catalog #E2291-58A
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:16,000
Western Blot: 0.5-1.5ug/ml, observed in human spleen lysates on ~110kD bands
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-QYLKKFSYRNAKND, from human ERAP2, at the internal region of the protein (NP_071745.1).
SpecificityRecognizes human ERAP2. Species sequence homology: Bovine and canine.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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