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You are here:Home » Antibodies » Abs to Enzymes, Isomerase » Anti -Endoplasmic Reticulum Protein 57 (ERp57, GRP58, PDIA3, Protein disulfide isomerase family A, member 3 [Homo sapiens], HGNC:4606, ERp60, ERp61, GRP57, HsT17083, P58, PI-PLC, 58kD microsomal protein, endoplasmic reticulum P58, glucose regulated protein, 58k

Anti -Endoplasmic Reticulum Protein 57 (ERp57, GRP58, PDIA3, Protein disulfide isomerase
family A, member 3 [Homo sapiens], HGNC:4606, ERp60, ERp61, GRP57, HsT17083, P58, PI-PLC,
58kD microsomal protein, endoplasmic reticulum P58, glucose regulated protein, 58k

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
ERp57, also known as GRP58, was cloned by three independent labs, all of which reported that the gene encodes a 505-amino acid protein that shares significant homology with the molecular chaperone protein disulfide isomerase (PDI). The ERp57 sequence was also shown to include a putative nuclear localization motif and an endoplasmic reticulum (ER) retention motif. Studies have shown that ERp57 functions together with calnexin and calreticulin as a molecular chaperone of glycoprotein biosynthesis within the ER.
Catalog #E2291-75H
Cellular Localization Endoplasmic reticulum
Positive Control A549 lysate
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in TBS, pH 7.2, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide: EEKPKKKKKAQEDL, representing the C-terminus of the human protein (residues 492-505), according to NP_005304.
SpecificitySpecies Crossreactivity: Crossreacts with Human. Expected to crossreact with Mouse, Rat, Rabbit and Hamster due to sequence homology.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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