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You are here:Home » Antibodies » Abs to Angiogenesis » Anti -Endostatin

Anti -Endostatin

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E
Endostatin is a potent inhibitor of endothelial cell proliferation, migration and angiogenesis. Recent study shows that endostatin induces tyrosine kinase activity and enhanced apoptosis in FGF-treated endothelial cells. Endostatin is currently being used in Phase I trails as an antitumor agent.
Catalog #E2900-03
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:3200 (0.312ug/ml)
Optimal dilutions to be determined by the researcher.
AA SequenceAla - Asp - Arg - Ala - Ala - Val - Pro - Ile - Val - Asn - Leu - Lys - Asp - Glu - Leu - Leu - Phe - Pro - Ser - Trp - Glu - Ala - Leu - Phe - Ser - Gly - Ser - Glu - Gly - Pro - Leu - Lys - Pro - Gly - Ala - Arg - Ile - Phe - Ser - Phe - Asp - Gly - Lys - Asp - Val - Leu - Arg - His - Pro - Thr - Trp - Pro - Gln - Lys - Ser - Val - Trp - His - Gly - Ser - Asp - Pro - Asn - NH2
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml (after reconstitution)
FormSupplied as a lyophilized powder from PBS. Reconstitute with 200ul sterile PBS.
PurityPurified by Protein A affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa52-114 of human Endostatin.
SpecificityRecognizes human Endostatin.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesJKC-362


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