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You are here:Home » Antibodies » Abs to Nitric Oxide » Anti -eNOS (Nitric Oxide Synthase, Endothelial, Constitutive NOS, cNOS, EC-NOS, Endothelial NOS, Nitric Oxide Synthase 3, NOS Type III, NOSIII, NOS3)

Anti -eNOS (Nitric Oxide Synthase, Endothelial, Constitutive NOS, cNOS, EC-NOS,
Endothelial NOS, Nitric Oxide Synthase 3, NOS Type III, NOSIII, NOS3)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Endogenous Nitric Oxide (NO) is a diffusible multifunctional second messenger that has been implicated in numerous physiological functions in mammals, such as blood vessel dilation, immune response and synaptic transmission enhancement. The NO is derived from L-arginine as the product of a complex enzymatic reaction catalyzed by a family of three NO synthase (NOS) proteins: nNOS (type I), iNOS (Type II), eNOS (type III). The endothelial NOS (eNOS) plays a critical role in controlling vascular tone, platelet aggregation, and cardiac myocyte function. It is strongly expressed in malignant mesothelioma, but is not associated with expression of vascular endothelial growth factor (VEGF) and its receptors. This phenomenon is different from what has been shown in non-neoplastic endothelial cells.
Catalog #E3010-84F
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 0.5-2ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceBovine
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to aa surrounding Serine 116 (TRPSPGP) of bovine NOS.
SpecificityRecognizes bovine NOS.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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