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You are here:Home » Antibodies » Abs to Endothelin » Anti -Endothelin, pan

Anti -Endothelin, pan

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Specifications

Clone Host Grade Applications
Monoclonal Mouse E
Endothelins (ET) show potent constrictor activity in vascular and non-vascular smooth muscle. This family of 21-amino acid peptides exists in at least three isoforms- ET-1, ET-2, and ET-3, and is produced in endothelial and epithelial cells. ET's can mediate biological effects in cells and tissues, and have been shown to bind to an ET receptor in the lung, kidney, heart, and liver.
Catalog #E3098-01P
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No8k43
HostMouse
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in PBS, pH 7.2.
PurityAscites
ImmunogenSynthetic peptide: CHLDIIW, corresponding to amino acids 15-21 of pan Endothelin.
SpecificityDetects endothelin (ET)-1, ET-2 and ET-3. This antibody shows no crossreactivity with the peptides ET(15-20) and ET(15-22). Species Crossreactivity: Crossreacts with Human.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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