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You are here:Home » Antibodies » Abs to Receptors » Anti -Endothelin A Receptor, aa410-422 (ET-A, ET1-Specific Type Endothelin Receptor, Ednra, ETA, ETRA)

Anti -Endothelin A Receptor, aa410-422 (ET-A, ET1-Specific Type Endothelin Receptor,
Ednra, ETA, ETRA)

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Specifications

Clone Host Grade Applications
Polyclonal Sheep Affinity Purified E B IP IH
The receptors for the endothelins are found on various tissues including lung and intestine. ETA receptor has been reported in a variety of tissues including placenta, uterus, testis, heart, adrenal gland, lung, kidney, ovary, skin, liver, bladder, large blood vessels, cerebellum, neurons, and meningioma tumor cells. A splice variant has been identified in melanoma (Zhang et al., 1998). ESTs have been isolated from libraries from the above-mentioned tissues.
Catalog #E3100
ApplicationsSuitable for Western Blot, ELISA, Immunoprecipitation and Immunohistochemistry. Other applications not tested.
Recommended DilutionsImmunohistochemistry: Suitable for paraffin embedded tissue.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.    
Clone TypePolyclonal
IsotypeIgG
HostSheep
SourceRat
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.5. No preservative added.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa410-422, QEQNHNTERSSHK of rat Endothelin A Receptor (C-Terminal-KLH). MW: 39kD.
SpecificityRecognizes rat Endothelin A Receptor. Tested using endothelin A receptor transfected COS cells for the expression of the 39kD segment of the cytoplasmic region of the receptor. Species Crossreactivity: human, mouse and sheep.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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