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You are here:Home » Antibodies » Abs to Transport Proteins » Anti -ENT1 (S254) (Equilibrative Nitrobenzylmercaptopurine Riboside-sensitive Nucleoside Transporter, Equilibrative NBMPR-sensitive Nucleoside Transporter,Nucleoside Transporter, es-type, Solute Carrier Family 29 Member 1, Slc29a1, Equilibrative Nucleoside Tran

Anti -ENT1 (S254) (Equilibrative Nitrobenzylmercaptopurine Riboside-sensitive Nucleoside
Transporter, Equilibrative NBMPR-sensitive Nucleoside Transporter,Nucleoside Transporter,
es-type, Solute Carrier Family 29 Member 1, Slc29a1, Equilibrative Nucleoside Tran

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
ENT1 is a member of the equilibrative nucleoside transporter family. It is a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies.
Catalog #E3225-01B
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:1,000
Western Blot: 1:50-1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to amino acid residues surrounding S254 of human ENT1 (KLH).
SpecificityRecognizes human ENT1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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