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You are here:Home » Antibodies » Antibodies-Disease Markers » Anti -Envoplakin

Anti -Envoplakin


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Clone Host Grade Applications
Monoclonal Mouse Supernatant E IH
Envoplakin is a precursor of epidermal cornified envelop under the plasma membrane of keratinocytes in the outer most layers of epidermis. It is expressed in keratinizing and nonkeratinizing stratified squamous epithelia but not in simple epithelia and non-epithelia. Loss of envoplakin function has been linked to the development of palmoplanter keratosis which is associated with the increased risk of esophegeal cancers.
Catalog #E3317
ApplicationsSuitable for use in Immunohistochemistry. Other applications have not been tested.
Recommended DilutionImmunohistochemistry (Formalin/paraffin): 1:5 for 60 min at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 1mM EDTA, pH 8.0, for 10-20 min followed by cooling at RT for 20 min. Detection may require use of a high-sensitivity detection system.
Optimal dilutions to be determined by the researcher.
Positive ControlSkin
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
Clone No5G96
ConcentrationNot determined
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide, before the addition of glycerol to 40%.
PurityTissue culture supernatant
ImmunogenN-terminal region of human envoplakin. Cellular Localization
SpecificityRecognizes human Envoplakin. The epitope is located at the N-terminus.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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