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You are here:Home » Antibodies » Abs to Tyrosine Kinases » Anti -Eck (EphA2, Mpk-5, Native Epithelial Cell Kinase, Eph receptor tyrosine kinase A2)

Anti -Eck (EphA2, Mpk-5, Native Epithelial Cell Kinase, Eph receptor tyrosine kinase A2)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified E FC IF
Eck belongs to the Eph tyrosine receptor familiy, the largest receptor tyrosine kinase family of transmembrane proteins. It encodes a 130kD transmembrane protein which is primarily found in adult human epithelial cells (1). Eph receptors and their ephrin ligands are important mediators of cell-cell communication and play roles in embryonic patterning, neuronal targeting, and vascular development during normal embryogenesis (2,3). The Eph family of receptor tyrosine kinases is frequently overexpressed in a wide variety of cancers and tumor cell lines. In particular, Eck is overexpressed in prostate, lung and colon cancers and 40% of breast cancers and it represents an attractive potential target for drug design (3,4).
Catalog #E3360-01J
ApplicationsSuitable for use in ELISA, Flow Cytometry and Immunofluorescence. Other applications not tested.
Recommended DilutionELISA: 1:200-1:400
Flow Cytometry: 1.2ug/10e6 cells
Immunnofluorescence: 1ug/10e6 cells
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 
Clone TypeMonoclonal
IsotypeIgG1
Clone No9E89
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified by Protein G affinity chromatography.
ImmunogenCDNA encoding human Eck.
SpecificityRecognizes native human Eck expressed on transfected cells.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesEph receptor tyrosine kinase A2


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