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You are here:Home » Antibodies » Abs to Tyrosine Kinases » Anti -Eck (EphA2, Mpk-5, Native Epithelial Cell Kinase)

Anti -Eck (EphA2, Mpk-5, Native Epithelial Cell Kinase)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
The Eph family of receptors is the largest known subfamily of receptor tyrosine kinases (RTK).
Eph RTKs and their ligands, the ephrins, are frequently overexpressed in a variety of cancers and tumor cell lines. One Eph family member, EphA2, is also overexpressed in a wide variety of cancers, including breast, small-cell lung and gastrointestinal cancers, melanomas, and neuroblastomas. The ephrin-Eph interactions are important in development, especially in cell-cell interactions involved in nervous system patterning and possibly in cancer.
Catalog #E3360-01K
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:500-2,000
Optimal dilutions to be determined by the researcher.
HybridomaF0 myeloma cells with spleen cells from Balb/c mice.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2b,k
Clone No9G465
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH7.4, 0.1% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to recombinant human EphA2 (559-976aa) purified from E. coli.
SpecificityRecognizes human EphA2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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