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You are here:Home » Antibodies » Abs to Tyrosine Kinases » Anti -Eck/EphA2 (EPHA2, EPH receptor A2, ARCC2, ECK, Ephrin type-A receptor 2, Epithelial cell kinase, Tyrosine-protein kinase receptor ECK) (PE)

Anti -Eck/EphA2 (EPHA2, EPH receptor A2, ARCC2, ECK, Ephrin type-A receptor 2, Epithelial
cell kinase, Tyrosine-protein kinase receptor ECK) (PE)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC
EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation.
Catalog #E3360-01L
ApplicationsSuitable for use in Flow Cytometry. Other applications have not been tested.
Recommended Dilutions
Flow Cytometry: 1:5. Dilute with PBS. 10ul labels 1x10e6 in 100ul.
Optimal dilutions to be determined by the researcher.
Positive ControlA431 cells
Storage and StabilityMay be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months after receipt at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.
Clone TypeMonoclonal
IsotypeIgG1
Clone No11C238
HostMouse
SourceHuman
ConcentrationNot Determined
FormSupplied as a liquid in PBS, 15mg/ml BSA, 0.1% sodium azide. Labeled with R-Phycoerythrin (PE).
PurityPurified by Protein G affinity chromatography
ImmunogenNative protein isolated by purification of phosphotyrosine-containing proteins (NP_004422)
SpecificityRecognizes human Epithelial Cell Kinase (Eck/EphA2).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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