Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Antibodies-Protein Kinases » Anti -Ephrin B3 (EFNB3, Ephrin B3 (EFL6, EPH-related receptor transmembrane ligand ELK-L3, EPH-related receptor tyrosine kinase ligand 8, Ephrin-B3, EPLG8, LERK8)

Anti -Ephrin B3 (EFNB3, Ephrin B3 (EFL6, EPH-related receptor transmembrane ligand ELK-L3,
EPH-related receptor tyrosine kinase ligand 8, Ephrin-B3, EPLG8, LERK8)


  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.


Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IP IH
Ephrins are the ligands which bind to the Eph receptor subfamily, the largest group of the receptor tyrosine kinase family. Both ephrins and Eph receptors are broadly expressed throughout the ectoderm, mesoderm and endoderm of vertebrate embryos. The interaction of ephrins with the appropriate Eph receptors has been implicated in a wide spectrum of functions in vertebrate morphogenesis, including the accurate migration of embryonic cells, formation of boundaries between structures (i.e. rhombomeres and somites) and the control of cytoskeletal changes which dictate cellular shape and adhesion during development. Two classes of ephrins exist: Class A ephrins are tethered to the membrane by a GPI linkage and bind primarily to EphA receptors; Class B ephrins contain a membrane-spanning region and bind predominantly to EphB receptors. Ephrin-B3 is a Class B protein. It has been shown to bind the EphB1, EphB2, EphB3 and EphA4 receptors.
Catalog #E3372
ApplicationsSuitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested.
Recommended DilutionsWestern Blot: 1-5ug/ml.
Immunoprecipitation: 5-10ug/ IP reaction
Immunohistochemistry (FFPE): 5-10ug/m. Enzyme digestion with pepsin is required. Confirmed with human tissue sections.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 
Clone TypePolyclonal
FormSupplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide derived from an internal sequence of the mouse ephrin-B3 protein.
SpecificityRecognizes mouse ephrin-B3 protein. Species Crossreactivity: human. Reactivity is con rmed with a chimeric protein consisting of the extracellular domain of human ephrin-B3 and the Fc region of human IgG1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

External Links