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Abs to Receptors, Tyrosine Kinase
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Anti -EPHB4 (Ephrin type-B Receptor 4, Tyrosine-protein Kinase Receptor HTK, Tyrosine-protein Kinase TYRO11, HTK, TYRO11)
Anti -EPHB4 (Ephrin type-B Receptor 4, Tyrosine-protein Kinase Receptor HTK,
Tyrosine-protein Kinase TYRO11, HTK, TYRO11)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Ascites |
E B IH IF |
|
| Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB4 binds to ephrin-B2 and plays an essential role in vascular development. | | | Catalog # | E3373-05Q | | Applications | Suitable for use in Immunofluorescence, ELISA, Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunofluorescence: 1:200-1:1000 | | ELISA: 1:10,000 | | Western Blot: 1:500-1:2000 | | Immunohistochemistry (Formalin fixed paraffin embedded): 1:200 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 5B5 | | Host | Mouse | | Source | Human | | Concentration | Not determined | | Form | Supplied as a liquid, 0.03% sodium azide. | | Purity | Ascites | | Immunogen | Recombinant corresponding to extracellular fragment of human EphB4 fused with hIgGFc tag expressed in HEK293. | | Specificity | Recognizes human EPHB4. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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