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(-)-Epigallocatechin Gallate (EGCG, (2R,3R)-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1[2H]- benzopyran-3,5,7-triol 3-(3,4,5-trihydroxybenzoate))
(-)-Epigallocatechin Gallate (EGCG, (2R,3R)-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1[2H]-
benzopyran-3,5,7-triol 3-(3,4,5-trihydroxybenzoate))
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| A polyphenol flavonoid that displays antitumor and antioxidant properties. Inhibits telomerase and DNA methyltransferase (DNMT) and blocks the activation of EGF receptors and HER-2 receptors. Also potently and specifically inhibits chymotrypsin-like activity of the proteasome in vitro (IC50= 86-194nM) and in vivo (IC50=1-10uM). | | | Catalog # | E3382-05A | | Solubility | DMSO or EtOH | | Molecular Weight | ~458.37 | | CAS Number | 989-51-5 | | Molecular Formula | C H O | | Molecular Weight | ~458.37 | | Purity | ~98% (HPLC) | | Concentration | Not determined | | Form | Supplied as a off-white to yellow solid. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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