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You are here:Home » Biochemicals » Biochem-Inhibitors » (-)-Epigallocatechin Gallate (EGCG, (2R,3R)-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1[2H]- benzopyran-3,5,7-triol 3-(3,4,5-trihydroxybenzoate))

(-)-Epigallocatechin Gallate (EGCG, (2R,3R)-2-(3,4,5-Trihydroxyphenyl)-3,4-dihydro-1[2H]-
benzopyran-3,5,7-triol 3-(3,4,5-trihydroxybenzoate))

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Specifications

A polyphenol flavonoid that displays antitumor and antioxidant properties. Inhibits telomerase and DNA methyltransferase (DNMT) and blocks the activation of EGF receptors and HER-2 receptors. Also potently and specifically inhibits chymotrypsin-like activity of the proteasome in vitro (IC50= 86-194nM) and in vivo (IC50=1-10uM).
Catalog #E3382-05A
SolubilityDMSO or EtOH
Molecular Weight~458.37
CAS Number989-51-5
Molecular FormulaC H O
Molecular Weight~458.37
Purity~98% (HPLC)
ConcentrationNot determined
FormSupplied as a off-white to yellow solid.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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