Anti -EPCAM (Epithelial Cell Adhesion Molecule, Ep-CAM, Adenocarcinoma-associated Antigen,
Cell Surface Glycoprotein Trop-1, Epithelial Cell Surface Antigen, Epithelial
Glycoprotein, EGP, Epithelial Glycoprotein 314, EGP314, hEGP314, KS 1/4 Antigen, KSA,
Major
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
B IP IH FC |
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| CD326 is known as Ep-CAM, tumor associated calcium signal transducer 1, epithelial cell surface antigen, epithelial glycoprotein 2, EGP2, adenocarcinoma associated antigen, and TROP1. CD326 is a type I transmembrane protein containing six disulfide bridges and one THYRO domain. This cell surface glycosylated 40kD protein is highly expressed in the bone marrow, colon, lung, and most normal epithelial cells and is expressed on carcinomas of gastrointestinal origin. Recently, it has been reported that CD326 expression occurs during the early steps of erythrogenesis. CD326 functions as a homotypic calcium-independent cell adhesion molecule and is believed to be involved in carcinogenesis by its ability to induce genes involved in cellular metabolism and proliferation. The CD326 antigen is an immunotherapeutic target for the treatment of human carcinomas. | | | Catalog # | E3405-50N | | Applications | Suitable for use in Western Blot, Flow Cytometry, Immunoprecipitation and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Flow Cytometry: 1:50-1:100 | | Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml | | Immunohistochemistry: Frozen | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | VU-ID9 | | Host | Mouse | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, 0.09% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | H69 cell line (small cell lung carcinoma). | | Specificity | Recognizes human EPCAM. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -EPCAM (Epithelial Cell Adhesion Molecule, Ep-CAM, Adenocarcinoma-associated Antigen, Cell Surface Glycoprotein Trop-1, Epithelial Cell Surface Antigen, Epithelial Glycoprotein, EGP, Epithelial Glycoprotein 314, EGP314, hEGP314, KS 1/4 Antigen, KSA, Major |
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