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You are here:Home » Antibodies » Abs to Cell Markers » Anti -Epithelial Specific Antigen (ESA, Epithelial Cellular Adhesion Molecule, EGP40, Ep-CAM, MK-1)

Anti -Epithelial Specific Antigen (ESA, Epithelial Cellular Adhesion Molecule, EGP40,
Ep-CAM, MK-1)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified B IH
Epithelial antigen is a membrane bound, glycosylated phosphoprotein anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It may play a role in adhesive functions and in cell to cell interactions, metastasis and signalling and provide a protective layer on epithelial surfaces. It is capable of direct or indirect interaction with actin cytoskeleton. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas.
Catalog #E3414-10A
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:100-1:750
Immunohistochemistry (formalin fixed paraffin embedded): 1:50-1:100
Immunohistochemistry: Frozen
Optimal dilutions to be determined by the researcher.
Positive ControlHuman lung cell line
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No11E181
HostMouse
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid, 0.05% sodium azide.
PurityPurified
ImmunogenSmall cell lung carcinoma. Cellular Localization: Cell membrane.
SpecificityRecognizes human Epithelial Antigen.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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