Anti -Epithelial Specific Antigen (ESA, Epithelial Cellular Adhesion Molecule, EGP40,
Ep-CAM, MK-1, GA733-2, KSA, 17-1A)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E B |
|
| The Ep-CAM (Epithelial Cell Adhesion Molecule), also termed as MK-1, GA733-2, KSA, 17-1A or EGP40, is a 40kD adhesion receptor, which is expressed in most simple, pseudostratified and transitional epithelia, but not in adult squamous epithelium (in humans). Its overexpession was suggested to be associated with enhanced epithelial proliferation on the majority of human carcinomas such as stomach, colon, pancreas, gall bladder, bile duct, mammary gland, breast and lung carcinoma. Thus Ep-CAM represents the best marker of tumor of epithelial lineage for diagnosis and therapy of cancer. | | | Catalog # | E3414-11E | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 5i255 | | Host | Mouse | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a lyophilized powder from PBS, pH 7.2. Reconstitute with 100ul sterile ddH2O. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Recombinant human Ep-CAM. | | Specificity | Recognizes human Ep-CAM. Does not react with mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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