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Specifications

Epothilone A is a microtubule inhibitor isolated from the myxobacteria, Sorangium cellulosum. Epothilone A acts by stabilising microtubule formation at the taxol binding site and causes cell cycle arrest at the G2/M transition, leading to cytotoxicity. Epothilone A is under investigation as an antitumor agent.
Catalog #	E3428-74
Source	Epothilone A from Sorangium cellulosum.
Molecular Weight	~493.7
Solubility	Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
Storage and Stability	Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number	152044-53-6
Molecular Formula	C26H39NO6S
Molecular Weight	~493.7
Purity	~98% (HPLC)
Concentration	Not determined
Form	Supplied as a white to off-white powder.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.