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You are here:Home » Biochemicals » Biochem-Inhibitors » Epothilone B (synthetic) (EpoB)

Epothilone B (synthetic) (EpoB)


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Epothilones are polyketide natural products that inhibit cancer cells by a mechanism similar to paclitaxel, and also are effective against paclitaxel-resistant tumours. Epothilone B is what is known as a microtubule stabilizer. When a cell divides, the chromosomes that will end up in each cell are separated by thin filaments called microtubules. Normally these microtubules then break down as the cell division progresses. This class of cytotoxic chemo drugs prevents that break down and thus prevents cells from completing division.
Catalog #E3428-75
Melting Point95-97°C
SolubilityChloroform, Dichloromethane, DMSO, Ethanol, Methanol
Method for Determining IdentityProton (CDCl3) NMR Spectroscopic and Mass Spectrometric Analysis
AtmosphereInert gas
Storage and StabilityMay be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Hygroscopic. Store under inert atmosphere.
CAS Number52044-54-7
Molecular FormulaC27H41NO6S
Molecular Weight507.68
FormWhite Solid
Important Note
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards 
All products should be handled by qualified personnel only, trained in laboratory procedures.
Alternate namesEpoB

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